Descending pathway facilitates undulatory wave propagation in Caenorhabditis elegans through gap junctions.

Descending alerts from the mind play vital roles in controlling and modulating locomotion kinematics. In the Caenorhabditis elegans nervous system, descending AVB premotor interneurons completely kind gap junctions with the B-type motor neurons that execute ahead locomotion. We mixed genetic evaluation, optogenetic manipulation, calcium imaging, and computational mannequining to elucidate the perform of AVB-B gap junctions throughout ahead locomotion. […]